Database

Creator

Date

Thumbnail

My List

See more

Search results

2 records were found.

Returning to sexual activity after an implantable cardioverter defibrillator (ICD) is a prominent concern of both patients and partners. Clinicians often do not advise patients about sex after an ICD, even though patients are concerned about safe return to sex and receiving an ICD shock. The purpose of this study was to describe the number and type of concerns of both patients and their intimate partners at the time of ICD implant, either for primary or secondary prevention of cardiac arrest.
Cytogenetic analysis of liposarcomas has demonstrated that translocation (12;16) (q13.3;p11.2) is characteristic of the myxoid subtype of this adipose tissue tumor. Our previous results suggested that the GLI gene is close to the translocation breakpoint on chromosome 12. We now describe a yeast artificial chromosome (YAC) that contains GLI and spans the chromosome 12 region involved in the t(12;16) breakpoint. This clone will permit rapid definition of the genetic region surrounding the breakpoint and allow isolation of the gene presumably affected by the translocation.